Bokbunja is popularly known to help men’s virility.

In May, the month of family, the demand for Mother’s Day gifts is soaring.

In the midst of this, interest is growing as it has been announced that the gallic acid component of Bokbunja seeds, a raw material of Bokbunja seed oil that can be obtained from raspberries, has a strong antiviral effect.

According to a study recently cited in the Journal of the American Society of Virology, a component that can strongly suppress viruses such as Corona 19 was found in bokbunja seed oil extracted from bokbunja seeds.

According to the research data of the Agriculture, Forestry and Food Technology Planning and Evaluation Institute, it was also found that gallic acid, which can be obtained from Korean Bokbunja seeds, has an antiviral function that suppresses the influenza virus, which is superior to Tamiflu.

In addition, Ajou University Advanced Biomedical Center Director Kim Soo-dong and Professor Park Chun-ho have confirmed the ability of bokbunja seed oil to neutralize the Corona 19 virus by producing strong neutralizing antibodies through animal experiments.

Gallic acid, a viral inhibitor that inhibits DNA function in Bokbunja seed extract, is based on a Histone Acetyl Transferase (HAT) inhibitory polyphenol complex.

In a study conducted by Professor Kim Hee-soo’s team at the Department of Dermatology at Catholic International St. Mary’s Hospital, the skin barrier improvement effect and autoimmune control ability were also revealed.

Ingesting bokbunja seeds in a normal way or grinding the bokbunja seeds themselves interferes with digestion and excretes the active ingredients without being able to absorb them.

It is known that if you take this in the form of oil, you can consume not only essential unsaturated fatty acids such as omega 3, but also polyphenol complex components such as gallic acid and anthocyanin at once.

On the other hand, bokbun seed oil is a health supplement that has excellent efficacy enough to be covered by major media.

Ajou University Advanced Medical Bio ICC Center research team, human white blood cell test results
It was found that Bokbunja seed oil, an oil extracted from black raspberries, has the effect of increasing immunity and killing cancer cells.

Ajou University Advanced Medical Bio ICC Center Director Kim Su-dong and Advanced Medical Bio ICC Professor Park Dong-wook research team administered white blood cells mixed with 10 μl of diluted Bokbunja seed oil to cancer cells. It was revealed on the 15th that many cancer cells were removed.

Then, as a result of administering bokbunja seed oil to human leukocytes, ‘interferon gamma (IFN-γ)’, a type of cytokine, increased by about 26% compared to the control group.

The research team administered bokbunja seed oil to cultured leukocytes for 6 hours. As a result of administration, the production of interferon gamma increased to about 125.8% compared to the control group not administered with Bokbunja seed oil.

Through this study, it was found that bokbunja seed oil promotes the secretion of immunoactive substances in cultured mouse immune cell line (RAW264.7 cell) and human immune cell line (THP-1 cell).

In the activation of immune cells secreted from human whole blood, secretion of immunoactive substances was promoted, and as a result, the death of target cancer cells was directly promoted.

In addition, the number of human natural killer cells (NK cells) in the culture system was increased.

Professor Kim said, “In conclusion, Bukbunja seed oil has the function of directly inducing the activation of immune cells and the increase of natural killer cells, and this can be seen as a possibility of using Bokbunja seed oil as a functional food ingredient to ‘increase immunity’.” “Through functional ingredient research, it is possible to research new drugs such as ‘anti-cancer and immune boosting agents,’” he said.

Bokbunja (覆盆子·Rubus coreanus MIQ) is named because eating this makes the urine stream stronger and overturns the urinary cavity. Because the fruit ripened in May of the lunar calendar is dark red, it is also called Oh Pyoja, Daemaek Mae, Sapjeon Pyo, and Disaster Pyo.

In old literature, such as , bokbunja is introduced as an antiperspirant, antipyretic, and tonic. In particular, it has been used as an aphrodisiac because eating bokbunja increases the amount of semen and urine. Antioxidants such as polyphenols and vitamin C contained in bokbunja improve health by removing free radicals, which are the main culprit in damaging the inner wall of blood vessels and causing arteriosclerosis, but the scientific basis for this is minimal.

However, research results have shown that the oil extracted from raspberries (Bokbunja seed oil) actually has the effect of increasing immunity and killing cancer cells.

Su-dong Kim, head of Advanced Medical Bio ICC Center at Ajou University, and Professor Dong-wook Park, Professor of Advanced Medical Bio ICC, said, “As a result of administering oil (Bokbunja seed oil) extracted from Korean Bokbunja seeds to human leukocytes, ‘interferon gamma (IFN-γ)’, a type of cytokine, was detected. increased by 26% compared to the control group.” Cytokines are signaling substances that control and stimulate the body’s immune system.

Center Director Kim’s research team also said, “As a result of injecting cancer cells into human leukocytes administered with Bokbunja seed oil, about half of the cancer cells were killed.”

For the research, the research team administered 10 μl of bokbunja seed oil diluted 1/50 of 0.2 μl (microliter, 1/100,000 L) to white blood cells, a collection of immune cells such as T cells, B cells, NK cells, and dendritic cells. did.

As a result, interferon gamma, a type of cytokine that commands the removal of pathogens and cancer cells, increased by 25.8% compared to the control group.

The research team also administered leukocytes mixed with 10 μl of bokbunja seed oil diluted in the same amount to cancer cells, and as a result, 48.2% of cancer cells were killed, 16% more cancer cells were removed than the control group (32%), and NK, an immune cell, was also killed. The amount of cells increased by about 6%.

Kim Su-dong, head of the ICC center who led the research, said, “As a result of this experiment, Bokbunja seed oil not only activates human immune cells to increase immunity, but also significantly increases the number of NK cells and enhances the ability to remove cancer cells.”